In this work we assessed the immune response induced by combinations of live (LcV) and heat-killed (LcM)Lactobacillus casei CRL 431 as adjuvants associated with pneumococcal protective A protein (PppA) in peripheral blood mononuclear cells (PBMCs). LcV, LcM and their combinations with PppA stimulated T, B and NK cells. Thus, all stimuli increased CD25 expression in T CD3 lymphocytes, highest activation being reached with the combinations of LcV or LcM with an antigen (PppA+LcV, PppA+LcM). Expression of CD19 B cells marker was significantly increased in almost all treatments compared with non-stimulated PBMCs, except for PppA. All treatments increased CD86 expression in the LT population, while in B cells only LPS, PppA+LcV and PppA+LcM inc...
Strategies for the development of new vaccines against Streptococcus pneumoniae infections try to ov...
Background - Economical and effective vaccines against Streptococcus pneumoniae (pneumococcus) are n...
Background - Economical and effective vaccines against Streptococcus pneumoniae (pneumococcus) are n...
This work analyzes the humoral and cellular immune responses induced by live (LcV) and heat-killed (...
Background: At present, available pneumococcal vaccines have failed to eradicate infections caused b...
Streptococcus pneumoniae is a highly important respiratory pathogen that causes infections in childr...
The present study analyzed whether nasal administration of viable and non-viable Lactobacillus casei...
The present study analyzed whether nasal administration of viable and non-viable Lactobacillus casei...
Lactococcus lactis NZ9000 is a non-pathogenic non-invasive bacterium extensively used for the delive...
This work demostrates that nonrecombinant Lactococcus lactis NZ, administered by the oral route at t...
Nisin-controlled gene expression was used to develop a recombinant strain of Lactococcus lactis that...
In the present work, we evaluated if oral immunization with the pneumococcal protective protein A (P...
Background: Polyinosinic:polycytidylic acid (Poly-IC) has been used as a viralstimulus to mimic in v...
The effect of Lactobacillus rhamnosus CRL1505 (Lr) on macrophages (Ma) and dendritic cells (DC) in t...
Strategies for the development of new vaccines against Streptococcus pneumoniae infections try to ov...
Strategies for the development of new vaccines against Streptococcus pneumoniae infections try to ov...
Background - Economical and effective vaccines against Streptococcus pneumoniae (pneumococcus) are n...
Background - Economical and effective vaccines against Streptococcus pneumoniae (pneumococcus) are n...
This work analyzes the humoral and cellular immune responses induced by live (LcV) and heat-killed (...
Background: At present, available pneumococcal vaccines have failed to eradicate infections caused b...
Streptococcus pneumoniae is a highly important respiratory pathogen that causes infections in childr...
The present study analyzed whether nasal administration of viable and non-viable Lactobacillus casei...
The present study analyzed whether nasal administration of viable and non-viable Lactobacillus casei...
Lactococcus lactis NZ9000 is a non-pathogenic non-invasive bacterium extensively used for the delive...
This work demostrates that nonrecombinant Lactococcus lactis NZ, administered by the oral route at t...
Nisin-controlled gene expression was used to develop a recombinant strain of Lactococcus lactis that...
In the present work, we evaluated if oral immunization with the pneumococcal protective protein A (P...
Background: Polyinosinic:polycytidylic acid (Poly-IC) has been used as a viralstimulus to mimic in v...
The effect of Lactobacillus rhamnosus CRL1505 (Lr) on macrophages (Ma) and dendritic cells (DC) in t...
Strategies for the development of new vaccines against Streptococcus pneumoniae infections try to ov...
Strategies for the development of new vaccines against Streptococcus pneumoniae infections try to ov...
Background - Economical and effective vaccines against Streptococcus pneumoniae (pneumococcus) are n...
Background - Economical and effective vaccines against Streptococcus pneumoniae (pneumococcus) are n...